Christopher M Overall Monday, April 22nd 2024, at 11:00 AM Paris Protein TAILS tell remarkable Tales: Purification of original and neo-N protein termini reveals pervasive proteolytic processing in proteomes Professor Chris Overall, is a Distinguished University Scholar of the University of British Columbia, Vancouver, a fellow of the Royal Society of Canada and of the […]
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Stefan Knapp Thursday, April 18th 2024, at 13.00 CET Development and characterization of chemical probes targeting the ubiquitin system Prof Stefan Knapp studied Chemistry at the University of Marburg (Germany) and at the University of Illinois (USA). He did his PhD in protein crystallography at the Karolinska Institute in Stockholm (Sweden) (1996) and continued his
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Shalini Padmanabhan Thursday, May 23rd 2024, at 13.00 CET The Michael J. Fox Foundation’s Research Strategy Shalini Padmanabhan is Vice President of Discovery and Translational Research at The Michael J. Fox Foundation for Parkinson’s Research. At the Foundation, she oversees a team of 8 other scientists and over 400 active projects focusing on the biological understanding
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Hans Brandstetter Thursday, April 04th 2024, at 13.00 CET The CD clan cysteine proteases: Unique structures, unique mechanisms and unique functions Hans Brandstetter received a Ph.D. in chemistry summa cum laude from the Technical University of Munich in 1994. He conducted postdoctoral research at the Massachusetts Institute of Technology and Harvard Medical School, Cambridge/Boston, and
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Francesca Ester Morreale Thursday, February 22nd 2024, at 13.00 CET Enabling targeted protein degradation in bacteria Francesca Ester Morreale is a Group Leader at the Francis Crick Institute, her research group focuses on establishing targeted protein degradation technology in bacteria. Ester obtained her PhD in Pharmaceutical Sciences in 2014 from the University of Messina (Italy). She
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Ambre SALA Thursday, February 15th 2024, at 13.00 CET Regulation of organismal proteostasis and stress resilience by reproductive and metabolic cues Ambre Sala is a group leader at the Institute for Integrative Biology of the Cell (I2BC), in Gif-sur-Yvette. She is interested in the mechanisms that orchestrate proteostasis in different cell types and their impact
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On October 30th, 2023, ProteoCure a workshop / webinar to present and discuss the possibilities for collaborative funding under Horizon Europe. This workshop included presentations by Marina MARTINEZ, Horizon Europe Programme Officer (CDTISOST-Brussels, Directorate of European Programmes and Regional Cooperation) and by ProteoCure members who shared their experience in participating in EU-funded projects: The presentations
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“Structure-based computational approaches for rational targeted protein degradation” Please log in to access the link to the webinar Dr. Juárez-Jiménez is a Lecturer in Physical Chemistry at the Faculty of Pharmacy of the University of Barcelona and the group leader of the Computational Molecular Design Lab. He obtained his PhD by the University of Barcelona in
Friday, April 21st 2023, at 16.00 Central European Time Please log in to find the link to the webinar Abstract: N-termini sequences are important sites for post-translational modifications, including limited proteolysis. Of the more than 500 proteases that are encoded by the human genome, only few can cleave a proline-containing peptide bond. The two intracellular
The next ProteoCure Targeted Protein Degradation seminar organised by the WG3 will be on Thursday 20th April 13:00 h (CET time). The speaker of this seminar will be Matthias Brand (CSO at Proxygen, https://proxygen.com). Please log in to see the link for this webinar. ******************* “Harnessing the power of phenotypic screening for glue degrader discovery” Matthias Brand