Recent publications by ProteoCure members

      2024

      Filippopoulou C, Thomé CC, Perdikari S, Ntini E, Simos G, Bohnsack KE, et al. Hypoxia-driven deSUMOylation of EXOSC10 promotes adaptive changes in the transcriptome profile. Cell Mol Life Sci. 2024;81: 58. doi:10.1007/s00018-023-05035-9

      2023

      Taibi V, Polo S, Maspero E. Monitoring HECT Ubiquitination Activity In Vitro. Methods Mol Biol. 2023;2602: 81–92. doi:10.1007/978-1-0716-2859-1_6
      Sengupta S, Pick E. The Ubiquitin-like Proteins of Saccharomyces cerevisiae. Biomolecules. 2023;13: 734. doi:10.3390/biom13050734
      Samra N, Jansen NS, Morani I, Kakun RR, Zaid R, Paperna T, et al. Exome sequencing links the SUMO protease SENP7 with fatal arthrogryposis multiplex congenita, early respiratory failure and neutropenia. J Med Genet. 2023;60: 1133–1141. doi:10.1136/jmg-2023-109267
      Sala-Gaston J, Costa-Sastre L, Pedrazza L, Martinez-Martinez A, Ventura F, Rosa JL. Regulation of MAPK Signaling Pathways by the Large HERC Ubiquitin Ligases. International Journal of Molecular Sciences. 2023;24: 4906. doi:10.3390/ijms24054906
      Saad S, Berda E, Klein Y, Issa S, Pick E. Strategies for Monitoring “Ubiquitin C-Terminal Hydrolase 1” (Yuh1) Activity. In: Rodriguez MS, Barrio R, editors. The Ubiquitin Code. New York, NY: Springer US; 2023. pp. 107–122. doi:10.1007/978-1-0716-2859-1_8
      Rosa JL. Regulation of Ubiquitin Family Signaling in Disease. International Journal of Molecular Sciences. 2023;24: 6735. doi:10.3390/ijms24076735
      Rodriguez MS, Barrio R, editors. The Ubiquitin Code. New York, NY: Springer US; 2023. doi:10.1007/978-1-0716-2859-1
      Quinet G, Génin P, Belgareh-Touzé N, Ozturk O, Weil R, Cohen MM, et al. Analysis of ATG8 Family Members Using LC3-Interacting Regions (LIR)-Based Molecular Traps. In: Rodriguez MS, Barrio R, editors. The Ubiquitin Code. New York, NY: Springer US; 2023. pp. 191–204. doi:10.1007/978-1-0716-2859-1_14
      Pelizzari-Raymundo D, Doultsinos D, Pineau R, Sauzay C, Koutsandreas T, Langlais T, et al. A novel IRE1 kinase inhibitor for adjuvant glioblastoma treatment. iScience. 2023;26. doi:10.1016/j.isci.2023.106687
      Pedrazza L, Martinez-Martinez A, Sánchez-de-Diego C, Valer JA, Pimenta-Lopes C, Sala-Gaston J, et al. HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling. Cell Death Dis. 2023;14: 1–11. doi:10.1038/s41419-023-05549-x
      Papendorf JJ, Ebstein F, Alehashemi S, Piotto DGP, Kozlova A, Terreri MT, et al. Identification of eight novel proteasome variants in five unrelated cases of proteasome-associated autoinflammatory syndromes (PRAAS). Frontiers in Immunology. 2023;14. Available: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1190104
      Matthiesen R, Rodriguez MS, Carvalho AS. A Computational Tool for Analysis of Mass Spectrometry Data of Ubiquitin-Enriched Samples. In: Rodriguez MS, Barrio R, editors. The Ubiquitin Code. New York, NY: Springer US; 2023. pp. 205–214. doi:10.1007/978-1-0716-2859-1_15
      Martínez-Férriz A, Gandía C, Pardo-Sánchez JM, Fathinajafabadi A, Ferrando A, Farràs R. Eukaryotic Initiation Factor 5A2 localizes to actively translating ribosomes to promote cancer cell protrusions and invasive capacity. Cell Commun Signal. 2023;21: 1–15. doi:10.1186/s12964-023-01076-6
      Martínez-Alonso M, Gandioso A, Thibaudeau C, Qin X, Arnoux P, Demeubayeva N, et al. A Novel Near-IR Absorbing Ruthenium(II) Complex as Photosensitizer for Photodynamic Therapy and its Cetuximab Bioconjugates. ChemBioChem. 2023;24: e202300203. doi:10.1002/cbic.202300203
      Ilter M, Schulze-Niemand E, Naumann M, Stein M. Structural Dynamics of Lys11-Selective Deubiquitinylase Cezanne-1 during the Catalytic Cycle. J Chem Inf Model. 2023;63: 2084–2094. doi:10.1021/acs.jcim.2c01281
      Guedes JP, Boyer JB, Elurbide J, Carte B, Redeker V, Sago L, et al. NatB-dependent acetylation protects procaspase-8 from UBR4-mediated degradation and is required for full induction of the extrinsic apoptosis pathway. bioRxiv; 2023. p. 2023.09.25.559278. doi:10.1101/2023.09.25.559278
      Gonzalez-Santamarta M, Ceccato L, Carvalho AS, Rain J-C, Matthiesen R, Rodriguez MS. Isolation and Mass Spectrometry Identification of K48 and K63 Ubiquitin Proteome Using Chain-Specific Nanobodies. In: Rodriguez MS, Barrio R, editors. The Ubiquitin Code. New York, NY: Springer US; 2023. pp. 125–136. doi:10.1007/978-1-0716-2859-1_9
      Elabd S, Pauletto E, Solozobova V, Eickhoff N, Padrao N, Zwart W, et al. TRIM25 targets p300 for degradation. Life Sci Alliance. 2023;6: e202301980. doi:10.26508/lsa.202301980
      Dubiel D, da Fonseca PCA, Valášek LS, Schulze-Niemand E, Naumann M. ZOMES: Cell physiology determined by PCI complexes and protein turnover. Biochimica et Biophysica Acta (BBA) – Molecular Cell Research. 2023;1870: 119402. doi:10.1016/j.bbamcr.2022.119402
      David A, Chazeirat T, Saidi A, Lalmanach G, Lecaille F. The Interplay of Glycosaminoglycans and Cysteine Cathepsins in Mucopolysaccharidosis. Biomedicines. 2023;11: 810. doi:10.3390/biomedicines11030810
      Creutznacher R, Schulze-Niemand E, König P, Stanojlovic V, Mallagaray A, Peters T, et al. Conformational Control of Fast Asparagine Deamidation in a Norovirus Capsid Protein. Biochemistry. 2023;62: 1032–1043. doi:10.1021/acs.biochem.2c00656
      Barroso-Gomila O, Merino-Cacho L, Muratore V, Perez C, Taibi V, Maspero E, et al. BioE3 identifies specific substrates of ubiquitin E3 ligases. Nat Commun. 2023;14: 7656. doi:10.1038/s41467-023-43326-8
      Barroso-Gomila O, Mayor U, Barrio R, Sutherland JD. SUMO-ID: A Strategy for the Identification of SUMO-Dependent Proximal Interactors. Methods Mol Biol. 2023;2602: 177–189. doi:10.1007/978-1-0716-2859-1_13
      Arnesen T, Aksnes H, Giglione C. Protein Termini 2022: central roles of protein ends. Trends in Biochemical Sciences. 2023;48: 495–499. doi:10.1016/j.tibs.2023.02.008

      2022

      Schulze-Niemand E, Naumann M, Stein M. Substrate-assisted activation and selectivity of the bacterial RavD effector deubiquitinylase. Proteins: Structure, Function, and Bioinformatics. 2022;90: 947–958. doi:10.1002/prot.26286
      Sala-Gaston J, Pedrazza L, Ramirez J, Martinez-Martinez A, Rawlins LE, Baple EL, et al. HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress. Cell Mol Life Sci. 2022;79: 548. doi:10.1007/s00018-022-04586-7
      Rivière F, Dian C, Dutheil RF, Monassa P, Giglione C, Meinnel T. Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation. Journal of Molecular Biology. 2022;434: 167843. doi:10.1016/j.jmb.2022.167843
      Nagamalleswari E, Bakshi K, Breucker J, Gschweitl M, González-Prieto R, Eisenhardt N, et al. UBC9 and EME1 sumoylation foster ribosomal DNA damage repair in CPT response. bioRxiv; 2022. p. 2022.04.11.487628. doi:10.1101/2022.04.11.487628
      Meinnel T, Giglione C. N-terminal modifications, the associated processing machinery, and their evolution in plastid-containing organisms. Journal of Experimental Botany. 2022;73: 6013–6033. doi:10.1093/jxb/erac290
      Mann G, Sulkshane P, Sadhu P, Ziv T, Glickman MH, Brik A. Antibody for Serine 65 Phosphorylated Ubiquitin Identifies PLK1-Mediated Phosphorylation of Mitotic Proteins and APC1. Molecules. 2022;27: 4867. doi:10.3390/molecules27154867
      Denamur S, Chazeirat T, Maszota-Zieleniak M, Vivès RR, Saidi A, Zhang F, et al. Binding of heparan sulfate to human cystatin C modulates inhibition of cathepsin L: Putative consequences in mucopolysaccharidosis. Carbohydrate Polymers. 2022;293: 119734. doi:10.1016/j.carbpol.2022.119734
      De Azevedo J, Mourtada J, Bour C, Devignot V, Schultz P, Borel C, et al. The EXTREME Regimen Associating Cetuximab and Cisplatin Favors Head and Neck Cancer Cell Death and Immunogenicity with the Induction of an Anti-Cancer Immune Response. Cells. 2022;11: 2866. doi:10.3390/cells11182866
      Bakshi K, Nagamalleswari E, Breucker J, Eisenhardt N, Tiwari R, González-Prieto R, et al. Multi-level monitoring of EME1-MUS81 in CPT induced nucleolar rDNA repair. bioRxiv; 2022. p. 2022.04.11.487769. doi:10.1101/2022.04.11.487769
      Badie A, Gaiddon C, Mellitzer G. Histone Deacetylase Functions in Gastric Cancer: Therapeutic Target? Cancers. 2022;14: 5472. doi:10.3390/cancers14215472
      Araújo SJ, Barrio R. Editorial: 17th Spanish Society for Developmental Biology Meeting: New Trends in Developmental Biology. Frontiers in Cell and Developmental Biology. 2022;10. Available: https://www.frontiersin.org/articles/10.3389/fcell.2022.897989
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