Francesca Ester Morreale Thursday, February 22nd 2024, at 13.00 CET Enabling targeted protein degradation in bacteria Francesca Ester Morreale is a Group Leader at the Francis Crick Institute, her research group focuses on establishing targeted protein degradation technology in bacteria. Ester obtained her PhD in Pharmaceutical Sciences in 2014 from the University of Messina (Italy). She […]
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Ambre SALA Thursday, February 15th 2024, at 13.00 CET Regulation of organismal proteostasis and stress resilience by reproductive and metabolic cues Ambre Sala is a group leader at the Institute for Integrative Biology of the Cell (I2BC), in Gif-sur-Yvette. She is interested in the mechanisms that orchestrate proteostasis in different cell types and their impact
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On October 30th, 2023, ProteoCure a workshop / webinar to present and discuss the possibilities for collaborative funding under Horizon Europe. This workshop included presentations by Marina MARTINEZ, Horizon Europe Programme Officer (CDTISOST-Brussels, Directorate of European Programmes and Regional Cooperation) and by ProteoCure members who shared their experience in participating in EU-funded projects: The presentations
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âStructure-based computational approaches for rational targeted protein degradationâ Please log in to access the link to the webinar Dr. JuĂĄrez-JimĂ©nez is a Lecturer in Physical Chemistry at the Faculty of Pharmacy of the University of Barcelona and the group leader of the Computational Molecular Design Lab. He obtained his PhD by the University of Barcelona in
Friday, April 21st 2023, at 16.00 Central European Time Please log in to find the link to the webinar Abstract: N-termini sequences are important sites for post-translational modifications, including limited proteolysis. Of the more than 500 proteases that are encoded by the human genome, only few can cleave a proline-containing peptide bond. The two intracellular
The next ProteoCure Targeted Protein Degradation seminar organised by the WG3 will be on Thursday 20th April 13:00 h (CET time). The speaker of this seminar will be Matthias Brand (CSO at Proxygen, https://proxygen.com). Please log in to see the link for this webinar. ******************* “Harnessing the power of phenotypic screening for glue degrader discovery” Matthias Brand
Friday, April 14th 2023, at 16.00 Central European Time Please log in to see the link Title: Dietary (poly)phenols as potential small molecules against chronic diseases Abstract: Breast cancer is the most commonly diagnosed cancer in women worldwide. Overall, this disease accounts for 15% of cancer deaths among the female population. Breast cancer has multifactorial
March 24th 2023, at 16.00 Central European Time Please log in to see the link for the webinar Prof. Robin Ketteler Design and Validation of Autophagy Targeting Chimera Targeted protein degradation (TPD) has opened new opportunities to investigate signalling pathways as a research tool, and as a unique therapeutic strategy using bifunctional chimeric small molecules.
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Prof. Alessio Ciulli, University of Dundee 23th March 2023, 13:30 (CET) Log in to see the link to attend the webinar Biography Alessio Ciulli holds the Personal Chair of Chemical Structural Biology at the School of Life Sciences, University of Dundee. He is the scientific founder of Amphista therapeutics, a biotech company spin-out of his
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Title: Function and dynamics of protein N-terminal modifications in health and disease. Spotlight on NatB-dependent acetylation and its role in apoptosis. N-terminal protein modifications (NPMs) are among the first and fastest responses to the cellular environment, influencing not only the modified protein but also cell, tissue, and whole organism phenotypes. One major NPM is N-terminal
Webinar: Dr Carmela Giglione (University Paris Saclay) Read More »